Gender differences in first episode psychotic mania.
Identifieur interne : 002679 ( Main/Exploration ); précédent : 002678; suivant : 002680Gender differences in first episode psychotic mania.
Auteurs : Sue M. Cotton [Australie] ; Martin Lambert ; Michael Berk ; Benno G. Schimmelmann ; Felicity J. Butselaar ; Patrick D. Mcgorry ; Philippe ConusSource :
- BMC psychiatry [ 1471-244X ] ; 2013.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Facteurs de risque (MeSH), Facteurs sexuels (MeSH), Femelle (MeSH), Humains (MeSH), Infractions sexuelles (psychologie), Jeune adulte (MeSH), Modèles logistiques (MeSH), Mâle (MeSH), Trouble bipolaire (épidémiologie), Trouble bipolaire (étiologie), Troubles liés à une substance (complications), Âge de début (MeSH).
- MESH :
- psychologie : Infractions sexuelles.
- épidémiologie : Trouble bipolaire.
- étiologie : Trouble bipolaire.
- complications : Adolescent, Adulte, Facteurs de risque, Facteurs sexuels, Femelle, Humains, Jeune adulte, Modèles logistiques, Mâle, Troubles liés à une substance, Âge de début.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Age of Onset (MeSH), Bipolar Disorder (epidemiology), Bipolar Disorder (etiology), Female (MeSH), Humans (MeSH), Logistic Models (MeSH), Male (MeSH), Risk Factors (MeSH), Sex Factors (MeSH), Sex Offenses (psychology), Substance-Related Disorders (complications), Young Adult (MeSH).
- MESH :
- complications : Substance-Related Disorders.
- epidemiology : Bipolar Disorder.
- etiology : Bipolar Disorder.
- psychology : Sex Offenses.
- Adolescent, Adult, Age of Onset, Female, Humans, Logistic Models, Male, Risk Factors, Sex Factors, Young Adult.
Abstract
BACKGROUND
The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients.
METHODS
Medical file audit assessment of 118 (male = 71; female = 47) patients with FEPM aged 15 to 29 years was undertaken on clinical and functional measures.
RESULTS
Males with FEPM had increased likelihood of substance use (OR = 13.41, p <.001) and forensic issues (OR = 4.71, p = .008), whereas females were more likely to have history of sexual abuse trauma (OR = 7.12, p = .001). At service entry, males were more likely to be using substances, especially cannabis (OR = 2.15, p = .047), had more severe illness (OR = 1.72, p = .037), and poorer functioning (OR = 0.96, p = .045). During treatment males were more likely to decrease substance use (OR = 5.34, p = .008) and were more likely to be living with family (OR = 4.30, p = .009). There were no gender differences in age of onset, psychopathology or functioning at discharge.
CONCLUSIONS
Clinically meaningful gender differences in FEPM were driven by risk factors possibly associated with poor outcome. For males, substance use might be associated with poorer clinical presentation and functioning. In females with FEPM, the impact of sexual trauma on illness course warrants further consideration.
DOI: 10.1186/1471-244X-13-82
PubMed: 23497439
PubMed Central: PMC3602146
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Cotton</name><affiliation wicri:level="4"><nlm:affiliation>Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 (35 Poplar Road), Parkville, Victoria, 3052, Australia. smcotton@unimelb.edu.au</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 (35 Poplar Road), Parkville, Victoria, 3052</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Lambert, Martin" sort="Lambert, Martin" uniqKey="Lambert M" first="Martin" last="Lambert">Martin Lambert</name></author><author><name sortKey="Berk, Michael" sort="Berk, Michael" uniqKey="Berk M" first="Michael" last="Berk">Michael Berk</name></author><author><name sortKey="Schimmelmann, Benno G" sort="Schimmelmann, Benno G" uniqKey="Schimmelmann B" first="Benno G" last="Schimmelmann">Benno G. Schimmelmann</name></author><author><name sortKey="Butselaar, Felicity J" sort="Butselaar, Felicity J" uniqKey="Butselaar F" first="Felicity J" last="Butselaar">Felicity J. Butselaar</name></author><author><name sortKey="Mcgorry, Patrick D" sort="Mcgorry, Patrick D" uniqKey="Mcgorry P" first="Patrick D" last="Mcgorry">Patrick D. Mcgorry</name></author><author><name sortKey="Conus, Philippe" sort="Conus, Philippe" uniqKey="Conus P" first="Philippe" last="Conus">Philippe Conus</name></author></analytic><series><title level="j">BMC psychiatry</title><idno type="eISSN">1471-244X</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Age of Onset (MeSH)</term><term>Bipolar Disorder (epidemiology)</term><term>Bipolar Disorder (etiology)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Logistic Models (MeSH)</term><term>Male (MeSH)</term><term>Risk Factors (MeSH)</term><term>Sex Factors (MeSH)</term><term>Sex Offenses (psychology)</term><term>Substance-Related Disorders (complications)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Adulte (MeSH)</term><term>Facteurs de risque (MeSH)</term><term>Facteurs sexuels (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Infractions sexuelles (psychologie)</term><term>Jeune adulte (MeSH)</term><term>Modèles logistiques (MeSH)</term><term>Mâle (MeSH)</term><term>Trouble bipolaire (épidémiologie)</term><term>Trouble bipolaire (étiologie)</term><term>Troubles liés à une substance (complications)</term><term>Âge de début (MeSH)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Substance-Related Disorders</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Bipolar Disorder</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Bipolar Disorder</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Infractions sexuelles</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Sex Offenses</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Trouble bipolaire</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Trouble bipolaire</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age of Onset</term><term>Female</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Risk Factors</term><term>Sex Factors</term><term>Young Adult</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Facteurs de risque</term><term>Facteurs sexuels</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Modèles logistiques</term><term>Mâle</term><term>Troubles liés à une substance</term><term>Âge de début</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>Medical file audit assessment of 118 (male = 71; female = 47) patients with FEPM aged 15 to 29 years was undertaken on clinical and functional measures.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Males with FEPM had increased likelihood of substance use (OR = 13.41, p <.001) and forensic issues (OR = 4.71, p = .008), whereas females were more likely to have history of sexual abuse trauma (OR = 7.12, p = .001). At service entry, males were more likely to be using substances, especially cannabis (OR = 2.15, p = .047), had more severe illness (OR = 1.72, p = .037), and poorer functioning (OR = 0.96, p = .045). During treatment males were more likely to decrease substance use (OR = 5.34, p = .008) and were more likely to be living with family (OR = 4.30, p = .009). There were no gender differences in age of onset, psychopathology or functioning at discharge.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Clinically meaningful gender differences in FEPM were driven by risk factors possibly associated with poor outcome. For males, substance use might be associated with poorer clinical presentation and functioning. In females with FEPM, the impact of sexual trauma on illness course warrants further consideration.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23497439</PMID><DateCompleted><Year>2013</Year><Month>06</Month><Day>28</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-244X</ISSN><JournalIssue CitedMedium="Internet"><Volume>13</Volume><PubDate><Year>2013</Year><Month>Mar</Month><Day>13</Day></PubDate></JournalIssue><Title>BMC psychiatry</Title><ISOAbbreviation>BMC Psychiatry</ISOAbbreviation></Journal><ArticleTitle>Gender differences in first episode psychotic mania.</ArticleTitle><Pagination><MedlinePgn>82</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/1471-244X-13-82</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Medical file audit assessment of 118 (male = 71; female = 47) patients with FEPM aged 15 to 29 years was undertaken on clinical and functional measures.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Males with FEPM had increased likelihood of substance use (OR = 13.41, p <.001) and forensic issues (OR = 4.71, p = .008), whereas females were more likely to have history of sexual abuse trauma (OR = 7.12, p = .001). At service entry, males were more likely to be using substances, especially cannabis (OR = 2.15, p = .047), had more severe illness (OR = 1.72, p = .037), and poorer functioning (OR = 0.96, p = .045). During treatment males were more likely to decrease substance use (OR = 5.34, p = .008) and were more likely to be living with family (OR = 4.30, p = .009). There were no gender differences in age of onset, psychopathology or functioning at discharge.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Clinically meaningful gender differences in FEPM were driven by risk factors possibly associated with poor outcome. For males, substance use might be associated with poorer clinical presentation and functioning. In females with FEPM, the impact of sexual trauma on illness course warrants further consideration.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Cotton</LastName><ForeName>Sue M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Orygen Youth Health Research Centre, University of Melbourne, Locked Bag 10 (35 Poplar Road), Parkville, Victoria, 3052, Australia. smcotton@unimelb.edu.au</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lambert</LastName><ForeName>Martin</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Berk</LastName><ForeName>Michael</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Schimmelmann</LastName><ForeName>Benno G</ForeName><Initials>BG</Initials></Author><Author ValidYN="Y"><LastName>Butselaar</LastName><ForeName>Felicity J</ForeName><Initials>FJ</Initials></Author><Author ValidYN="Y"><LastName>McGorry</LastName><ForeName>Patrick D</ForeName><Initials>PD</Initials></Author><Author ValidYN="Y"><LastName>Conus</LastName><ForeName>Philippe</ForeName><Initials>P</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>03</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Psychiatry</MedlineTA><NlmUniqueID>100968559</NlmUniqueID><ISSNLinking>1471-244X</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017668" MajorTopicYN="N">Age of Onset</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001714" MajorTopicYN="N">Bipolar Disorder</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016015" MajorTopicYN="N">Logistic Models</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012737" MajorTopicYN="N">Sex Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012742" MajorTopicYN="N">Sex Offenses</DescriptorName><QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019966" MajorTopicYN="N">Substance-Related Disorders</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>01</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>01</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>3</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>3</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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Butselaar</name><name sortKey="Conus, Philippe" sort="Conus, Philippe" uniqKey="Conus P" first="Philippe" last="Conus">Philippe Conus</name><name sortKey="Lambert, Martin" sort="Lambert, Martin" uniqKey="Lambert M" first="Martin" last="Lambert">Martin Lambert</name><name sortKey="Mcgorry, Patrick D" sort="Mcgorry, Patrick D" uniqKey="Mcgorry P" first="Patrick D" last="Mcgorry">Patrick D. Mcgorry</name><name sortKey="Schimmelmann, Benno G" sort="Schimmelmann, Benno G" uniqKey="Schimmelmann B" first="Benno G" last="Schimmelmann">Benno G. Schimmelmann</name></noCountry><country name="Australie"><region name="Victoria (État)"><name sortKey="Cotton, Sue M" sort="Cotton, Sue M" uniqKey="Cotton S" first="Sue M" last="Cotton">Sue M. Cotton</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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